Cochrane South Africa leads innovative research to bridge the gap between vaccine development and real-world public health outcomes. This portfolio focuses on improving vaccine delivery systems, addressing structural barriers, and enhancing equitable access across Africa.

Key areas of work include:

Missed Opportunities for Vaccination: Identifying and addressing gaps where eligible individuals are not vaccinated, to improve coverage and protect vulnerable populations.
Evidence-Informed Decision-Making: Strengthening the capacity of healthcare systems and policymakers through data-driven tools that guide vaccine strategy, logistics, and communication.
Demand-Side Interventions: Developing practical tools and frameworks to understand and reduce vaccine hesitancy, helping build public trust and uptake.
Knowledge Platforms: Creating accessible, evidence-based repositories to inform vaccination program design and adaptation across the continent.

By addressing both the supply-side and demand-side challenges in immunisation, Cochrane SA equips stakeholders with the knowledge necessary for effective, inclusive, and sustainable vaccine implementation strategies.

Portfolio lead: Duduzile Ndwandwe (duduzile.ndwandwe@mrc.ac.za) supported by Anelisa Jaca (anelisa.jaca@mrc.ac.za )