This portfolio represents a coherent and evolving programme of research activities focused on advancing the design, conduct, analysis, reporting, and interpretation of evidence synthesis methods. In line with the Cochrane Collaboration’s mission, it aims to enhance the rigour, transparency, efficiency, and usability of systematic reviews and related outputs to better inform health decisions.

Key activities include:

• Developing and evaluating risk-of-bias tools (e.g. RoB 2, ROBINS-I)
• Methods for incorporating non-randomised studies
• GRADE methodology and decision frameworks
• Rapid review methods and automation tools
• Qualitative evidence synthesis methodology
• Equity considerations in evidence synthesis
• Living systematic reviews and updating strategies