Cochrane South Africa manages two clinical trial registry databases that are hosted within the South African Medical Research Council (SAMRC). The Pan African Clinical Trials Registry (PACTR) which is a regional registry of the WHO-ICTRP network was initially established as the Aids, TB, and Malaria trial Registry (ATM registry) in 2007 and relaunched in 2009 as PACTR to include registration of trials studying all diseases or conditions. PACTR is the only African primary registry in the WHO-ICTRP network. The South African National Clinical Trial Register (SANCTR) was established following a call by the South African Department of Health Minister to have clinical trials registered on a public register in 2005 and was redeveloped and hosted by the SAMRC in August 2020. The two registries collect the WHO-required datasets, which provide sufficient information to identify each trial in a publicly accessible domain uniquely.

Portfolio lead: Duduzile Ndwandwe (duduzile.ndwandwe@mrc.ac.za) supported by Lindi Mathebula (lindi.mathebula@mrc.ac.za)